However, one study demonstrated that chronic THC treatment in adult mice impairs performance in the object recognition task for 4 days following the last THC injection and these deleterious effects were shown to be prevented by a pre-treatment with Temsirolimus, an mTOR inhibitor, suggesting a role for mTOR in the THC-induced long-lasting memory impairment (Puighermanal et al., 2013). The gene discussed is MTOR; the disease is memory impairment.