These include caveolin 1 [which directly binds DLC1 (Figure S5) and contributes to its tumor suppressive roles (Du et al. 2012)], CDKN1B [which is an inhibitor of and directly binds to CDK6 (Soos et al. 1996)], and cyclin D1 [which forms a complex with CDK6 (Weinberg 2007)]. The gene discussed is CDKN1B; the disease is neoplasm.