HP and bacterial infectious disease: The SAA has different functions but mainly modulates innate immune reactions and in particular the migration of monocytes and neutrophils, whereas Hp has anti-inflammatory properties; LBP is triggered by bacterial infections and helps in the neutralization of LPS and in the activation of a cascade of reactions that leads to the release of cytokines, among which IL-6, that are necessary for the activation of the immune system [10,46,47].