MAP3K1 and cancer: Overall, 63% (12/19) of the samples were found to display mutations in additional cancer genes including PIK3CA in 37% (7/19), TP53 in 5% (1/19), GATA3 in 11% (2/19), MAP3K1 11% (2/19), and MAP3K4 in 21% (4/19) (Figure 1D and Supplementary Table 8).