The prognostic value of this molecule in feline carcinomas is still controversial: while no statistically significant association between E-cadherin expression and tumour histological grade has been found [31], one study demonstrated a negative correlation between E-cadherin expression and regional lymph node metastases at the time of diagnosis [31], however another revealed no correlation between the expression of E-cadherin and survival, recurrence or metastases [19]. Here, CDH1 is linked to neoplasm.