SOCS1 and ovarian hyperstimulation syndrome: Inspired by the hypothesis that SOCS-1 might modulate the negative effect of hCG on IL-2 production in OHSS patients, we designed the present pilot exploratory case series, aimed to evaluate the expression of IL-2 and its suppressor, SOCS-1, in the PBMCs of patients suffering from severe OHSS, and to examine whether their expressions differ when compared to PBMCs originated from normal early pregnant women (without OHSS).