This suggestion of two separate processes in DM1 evolution has also been recently described in a study that analysed cerebrospinal fluid levels of three biomarkers in patients with DM1, namely total tau (T-tau), phosphorylated tau (P-tau) and 42-amino-acid form of ß-amyloid (Aß42). This evidence concerns the gene MAPT and myotonic dystrophy type 1.