There are several association studies showing that VEGF -2578C > A, -1498T > C (-460T > C), -1154G > A, -634G > C (405G > C), and 936C > T correlate with CRC risk [6], and the following alleles: VEGF -2578A, -1498T, -1154A, -634C, and 936T: are associated with reduced VEGF expression [25–27]. Here, VEGFA is linked to colorectal carcinoma.