TNF and inflammatory bowel disease: Among AS patients anti-TNF treatment (HR 1.6, 95% CI 1.2 to 2.1), IBD (2.3 (95%CI 1.7 to 3.3), and a previous history of NL (16.4 (95%CI 11.5 to 23.4)) were identified as predictors of NL during follow-up (table 3).