The levels of MMP-11 were significantly higher in patients with advanced tumor extent (T2: 16.10±9.74 ng/mL, T3: 18.58±10.82 ng/mL and T4: 17.16±10.39 ng/mL) when compared with T1 (11.48±6.56 ng/mL) patients (Figure 1B). Here, MMP11 is linked to neoplasm.