In the right atrium of patients with AF, nuclear NF-AT3 levels were correlated with PICP (p <0.01) and TGF-β1 levels (p <0.01), while nuclear NF-AT4 levels correlated with PINP (p <0.01) and PICP levels (p <0.05 (Table 5). This evidence concerns the gene NFATC4 and atrial fibrillation.