APOE and familial hypercholesterolemia: Evaluation of the 24-hour urine protein excretion (Figure 2B) revealed that neither hypercholesterolemia (ApoE Sham: 26.4 ± 3.5 mg/24 h) nor ovariectomy (C57 OVX: 33.7 ± 4.7 mg/24 h) resulted in altered proteinuria when compared to C57 Sham (25.1 ± 5.7 mg/24 h).