CDH2 and pancreatic adenocarcinoma: To further evaluate the role of ETS-1 during EMT, we inhibited ETS-1 expression with an ETS-1-specific shRNA and assessed its effects on the expression of N-cadherin, E-cadherin and VEGF in the Panc-1 cell line, a highly metastatic epithelial-pancreatic adenocarcinoma cell line.