Another gene-environment interaction that has been studied is the CCAAT/enhancer-binding protein alpha (CEBPA) rs12691 SNP and 6 diabetes-related traits (fasting glucose and insulin levels, disposition index, insulin sensitivity index, HOMA-insulin resistance (HOMA-IR) index and acute insulin response to glucose) following 12 weeks of 4 dietary interventions (i.e., high SFA diet, high MUFA diet, low-fat diet and low-fat-high-n-3 PUFA diet). The gene discussed is INS; the disease is diabetes mellitus.