In this regard, one study focused on the associations between SNPs rs1801260, rs3749474 and rs4580704 with 3 diabetes-related traits (i.e., insulin concentration, HOMA-IR index and quantitative insulin sensitivity check (QUICKI) index) following one year of dietary intervention (i.e., 35% fat, 22% MUFAs vs. 28% fat, 12% MUFAs). Here, INS is linked to diabetes mellitus.