ADIPOQ and type 2 diabetes mellitus: In oriental individuals, the T allele of common adiponectin SNP276 G > T and SNP45 G > T has been associated with T2DM in Japanese individuals [64], whereas only SNP276 G > T has been associated with T2DM in Taiwanese patients [65]; the G allele of both SNPs has been associated with several components of the metabolic syndrome in non-obese and non-diabetic Korean men [66] (Table 2).