SLC4A1 and Diaphyseal sclerosis: CA2 also has a physical interaction with SLC4A1 and a functional similarity for a biological process with TNFSF11. In agreement with the whole set of HPO annotations for CA2, the most specific clinical features for this gene include: distal renal tubular acidosis (HP:0008341), extramedullary hematopoiesis (HP:0001978), periodic hypokalemic paresis (HP:0008153), optic nerve compression (HP:0007807), elevated serum acid phosphatase (HP:0003148) and diaphyseal sclerosis (HP:0003034).