IL17A and Alzheimer disease: Superantigens secreted from S. aureus in AD skin further stimulate keratinocytes to produce TSLP and induce polyclonal activation of T cells via binding directly to the common variable β (vβ) chains of T-cell receptors [83–85], which results in exaggerated Th2 inflammatory responses leading to worsening AD, and this can also promote systemic Th2 responses and allergic lung inflammation through an IL-17A dependent mechanism [59].