While in situ hybridization studies have spotted its detection only in stromal cells [1, 17], another study, based on differentially expressed gene analyses by GeneChip hybridization, has pointed to the over-expression of COL11A1 mRNA in tumour epithelia [13]; very recently, Cheon et al.[48] have reported, also through in situ hybridization and immunohistochemistry with the DMTX1/1E8.33 mAb of serous ovarian cancer, that “COL11A1 expression was confined to intra/peritumoral stromal cells and rare foci of tumor epithelial cells”. The gene discussed is COL11A1; the disease is ovarian serous adenocarcinoma.