BRCA1 and breast cancer: The presence of the 17q25.3 gain was assessed in 9 BRCA1-mutated non-TNBC (7 luminal A and 2 HER2+) and in a cohort of 78 BC unscreened for BRCA1 mutation (20 luminal A, 22 luminal B, 21 HER2+ and 15 TNBC) (Table 1).