Six SNPs (rs406113 and rs974334 on the glutathione peroxidase 6 (GPX6) gene, rs1052133 on the 8-oxoguanine DNA glycosylase (OGG1) gene, rs2284659 on the superoxide dismutase 3 (SOD3) gene, rs4135225 on the thioredoxin (TXN) gene and rs207454 on the xanthine dehydrogenase (XDH) gene) are associated with variations in the predisposition to BC. This evidence concerns the gene XDH and breast cancer.