We have previously conducted a genome-wide association study (GWAS) on SCLC to identify genetic variants influencing length of survival in patients and found that the rs1820453T > G SNP, located in the promoter region of the YAP1 gene which creates a transcription factor binding site and results in down-regulation of YAP1 expression, is significantly associated [4]. Here, YAP1 is linked to small cell lung carcinoma.