We analysed the TCR Vβ spectratype within both CD4 and CD8 T cells (isolated from MOPC-sensitized or Balb/c-sensitized B10.D2 mice), as our previous results support a role of CD8 T cells in the GvM effect, whereas chronic GvHD in the B10.D2→Balb/c model is mainly dependent on CD4 T cells [28], [29]. The gene discussed is CD8A; the disease is graft versus host disease.