For activated CD4 T cells, an increase in percentages and absolute counts was also observed in Allo-MM mice at sacrifice, but this increase was much smaller compared to that of CD8 T cells (fold-increase in T-cell counts for Allo-MM vs. Auto-MM: CD8 T cells: 8.2x; activated CD8 T cells: 12x. This evidence concerns the gene CD4 and Miyoshi myopathy.