This result suggests that sensitization with myeloma cells could lead to increased alloreactivity in this model due to the presence of shared antigens between both allogeneic Balb/cJ and MOPC315.BM cells, as demonstrated by the presence of overlapping CDR-3 size skewed bands in both CD4 and CD8 T-cell populations (Table 1). The gene discussed is CD4; the disease is plasma cell myeloma.