Comparison of the skewed CDR3-size lengths of CD4 or CD8 T cells isolated from splenocytes of B10.D2 mice sensitized with myeloma or Balb/cJ cells, compared to non-sensitized B10.D2 control mice (skewed if mean peak area> mean+3SD of corresponding control peak). The gene discussed is CD8A; the disease is plasma cell myeloma.