In the CD8 T-cell-depleted group, 4 out of 6 mice (66.7%) showed strong bioluminescence signals and myeloma symptoms after transplantation, whereas in the standard Allo-MM group a bioluminescence signal was only observed in one out of 18 mice after transplantation (5.6%, p<0.01). The gene discussed is CD8A; the disease is Miyoshi myopathy.