We selected 6 loci (Table 2, Figure 5A) displaying significant differential cirDNA modification in the microarray analysis (Rab3a, Atp6v0c, B4galnt1, Slc1a1, Ttl and Krt15) and whose corresponding genes have been reported as associated to lung cancer phenotypes (Table 2). The gene discussed is RAB3A; the disease is lung carcinoma.