Protein levels by both methods were found to be highly significantly correlated with STMN1 mRNA level (p<0.001 and p=0.008, respectively) (Figure 2), supporting that higher level of stromal contamination in CAH is unlikely to be the sole explanation for the differences in PI3K activation levels demonstrated for CAH and EEC. Here, PIK3CA is linked to congenital adrenal hyperplasia.