VPS45 and infection: MPCaMV YXXΦ motifs appeared to be essential for infectivity and, consistent with endocytic trafficking being important for infection, CaMV did not infect ben1(min7) and ben2(vps45) plants, two Arabidopsis mutant lines with defects in the trafficking of early endosomes through the TGN/EE, a dynamic tubular-vesicular trans-Golgi network in plant cells that is the main sorting hub for secretory and vacuolar traffic, as well as the destination for endocytic cargo (Zeenko et al., 2002).