Moreover, differential expression of genes with a postulated role in the formation of neural projections, such as AHI1, have been implicated in psychiatric disorders such as SCZ (Amann-Zalcenstein et al., 2006; Ingason et al., 2010; Slonimsky et al., 2010), and ASD (Alvarez Retuerto et al., 2008) as well as in modulation of emotional phenotypes and stress vulnerability in relevant Ahi1 knockout mouse models (Xu et al., 2010; Lotan et al., 2014). The gene discussed is AHI1; the disease is psychiatric disorder.