In our study, expression levels of few important candidates of coagulation system and hemostasis including antithrombin-III, alpha-2-antiplasmin, vitamin K-dependent protein S, fibrinogen alpha chain, plasminogen, alpha-2-macroglobulin and coagulation factor XII were found to be elevated in the different grades of meningiomas (Table 1 and S6). This evidence concerns the gene F12 and meningioma.