With this in mind, we assessed key transiently activated neural transcription factors (MATH1, NHLH1), and other temporally activated genes (NEUROD1, NHLH2, NFIB, LPPR4, DPYSL3, NEUROD2) expressed throughout granule neuron differentiation, in the medulloblastoma subgroups (Fig. 3c). This evidence concerns the gene NEUROD1 and medulloblastoma.