In contrast to NAb targeting epitopes of gB, gH/gL, or gM/gN that neutralize HCMV infection of fibroblasts or EC with moderate potency, NAb that recognize conformational epitopes of gH/gL-PC neutralize HCMV infection of EC with unusually high potency [41]. This evidence concerns the gene PPP1R3A and cytomegalovirus infection.