In view of the IHC staining showing that elevated FOXM1 expression is associated with poor prognosis and thus chemoresistance, a pair of established ovarian cancer cell line sensitive and resistant to paclitaxel, namely SKOV-3 and SKOV3-TR respectively, were used to study the effect of paclitaxel treatment on the expression of FOXM1. The gene discussed is FOXM1; the disease is ovarian cancer.