CDK7 and endometrial carcinoma: To reveal the association between CDK7 and platinum resistance in endometrial carcinoma cells, CDK7-423 was selected to specifically reduce CDK7 expression in HEC-1-A endometrial carcinoma cells, and the MTT cytotoxicity assay, flow cytometry and Hoechst/PI double-staining immunofluorescence microscopy were used to detect changes in cisplatin sensitivity.