Furthermore, we found that knockdown of EGR4 by siRNA suppressed the proliferation of PC14PE6 NSCLC cells (Figure S5), but did not find the inhibitory effects of EGR4 knockdown on its downstream genes, SAMD5, RAB15, SYNPO and DLX5 expression in PC14PE6 cells (data not shown). The gene discussed is DLX5; the disease is non-small cell lung carcinoma.