HDAC4 and obesity due to melanocortin 4 receptor deficiency: Other two genes, CAPN10 and HDLBP, that are located distal to HDAC4, were also associated with obesity [27] and deleted for patient 5 carrying a 2q37 deletion that is distal to and did not include HDAC4. Another obese patient with a terminal deletion distal to HDAC4 was reported by Williams et al. [3].