Other studieshave shown that sputum levels of IL-5 trend higher in patients with eosinophilic asthma,whereas those of IL-8 trend higher in patients with non-eosinophilic asthma.(29,42) There is evidence that IL-5 is detectable in the induced sputum of asthmapatients and that sputum levels of IL-5 are higher in patients with severe asthma thanin those with mild-to-moderate asthma.(10,42). Here, CXCL8 is linked to asthma.