PCNA and hepatocellular carcinoma: As compared to that in the DEN + NCD group (10 week: 55.71 ± 8.28 cells/field; 12 week: 56.57 ± 10.26 cells/field; 14 week: 62.11 ± 8.45 cells/field), PCNA-positive HCC cells in the DEN + HFD group were much less (10 week: 34.29 ± 5.94 cells/field; 12 week: 41.14 ± 7.06 cells/field; 14 week: 60.50 ± 11.68 cells/field) at the time points of 10 and 12 week (P < 0.05, Figure 3B).