The values of BALF IL-1β, TNF-α, IL-8 and the ratios of IL-1β/IL-10, TNF-α/IL-10, IL-8/IL-10, IL-1β/TGF-β1, TNF-α/TGF-β1, IL-8/TGF-β1 and IL-1β/IL-1RA were significantly higher in mixed PJP than in pure PJP patients. The gene discussed is IL1B; the disease is pneumocystosis.