We also found that IL-5, which plays a critical role in the differentiation, infiltration, and activation of pulmonary eosinophils [37], was down-regulated by E. granulosus infection.These findings demonstrate that an E. granulosus infection has the potential to counteract allergic asthma-associated eosinophilic airway inflammatory responses. The gene discussed is IL5; the disease is allergic asthma.