Macroscopically visible metastases in lung/liver (Figure 3a), along with increased frequency of tumor cells cloned from DLN (Figure 3b), was seen in EMT6 tumor injected mice receiving immunotherapy and anti-CD4 relative to mice receiving control Ig (see also [9])-as noted in Figure 1, where other immunotherapy-treated (but no anti-CD4) EMT6 groups were sacrificed at d18/26 (not 90 d as shown) there were, as expected, no metastases seen. Here, CD4 is linked to neoplasm.