The CCND1 G870A polymorphism showed significant difference between NPC patients and healthy controls in genotype comparison (AA vs. GG: OR = 2.291, 95% CI 1.086–4.833, p = 0.030; AG vs. GG: OR = 2.788, 95% CI 0.350–5.756, p = 0.006; AA/AG vs. GG: OR = 2.566, 95% CI 1.275–5.165, p = 0.008; AA vs. AG/GG: OR = 0.991, 95% CI 0.644–1.526, p = 0.968,Table 2). This evidence concerns the gene CCND1 and nasopharyngeal carcinoma.