Recently, the use of 5-fluorouracil [5-FU] has been investigated in cases with severe types of endometriosis with limited success.Future TherapiesDue to the relatively poor efficacy of hormonal therapy for endometriosis, several other experimental therapies are currently undergoing clinical trial, such as Mifepristone, a selective progesterone receptor modulator, therapies designed to exploit the characteristics of endometriotic cells as potential drug targets such as anti-angiogenic therapy. The gene discussed is PGR; the disease is endometriosis.