EHMT2 and Atrioventricular canal defect: Nkx2.5-Cre driven dual function loss of GLP and G9a (GLP-KO/G9a-KD) mice showed reduction of H3K9me2 level in CM and atrioventricular septal defects, but not in single either GLP or G9a function loss (Inagawa et al., 2013).