GLP-1 and its analogues, in addition to their insulin-tropic action in alleviating hyperglycemia, have beneficial effects in protecting from the progressive impairment of pancreatic β-cell function, preserving β-cell mass and suppressing glucagon secretion, gastric emptying and appetite, all of which are characteristics that could prove beneficial for the management of diabetes [7]. This evidence concerns the gene GLP1R and diabetes mellitus.