Among the 37 common SNPs in seven TF pathway genes (TF, F2, F5, F7, F10, TFPI and EPCR), six SNPs in three separate genes were found to be associated with breast cancer: four intronic SNPs in the F5 gene (rs12120605, rs6427202, rs9332542 and rs6427199), one in the upstream region of the F10 gene (rs3093261), and one intronic SNP in the EPCR gene (rs2069948). Here, TFPI is linked to breast cancer.