EPHX2 and breast cancer: The median 14,15-EET level was 2.5-fold higher in BC tissue than adjacent noncancerous tissue (4145.9 [IQR 1299.8-6500.0] vs. 1634.4 [1092.5-3844.7] ng/mg protein; p =0.01) (Figure 1A) and the median ratio of 14,15-EET to episomal 14,15-DHET was higher in BC tissue than noncancerous tissue (0.80 [0.64-0.85] vs. 0.58 [0.37-0.75]; p <0.001) (Figure 1B), with no difference in total 14,15-DHET level (including episomal and transformed DHET from 14,15-EET by sEH) (Figure 1C).