Although the results of the migration analyses may in part be explained by a reduction in cell number rather than a change of cell migration ability, the analysis of mRNA levels confirmed down-regulation of cell motility-associated genes such as MAPK12 [42], PLCG2 [43] and NCF4 [44] in all three FOXP1 transgenic neuroblastoma cell lines analyzed. This evidence concerns the gene PLCG2 and neuroblastoma.