While our study suggests that subjects with HLA-B*14 (with significantly lower CD4 T-cell counts at 12 months and a trend of lower levels of CD4 T-cells at baseline and at 6 months and higher VL) progressed faster to disease, others found significant associations between allele and low disease progression [56] and that the allele had enhanced HIV infection [57]. This evidence concerns the gene HLA-B and HIV infectious disease.