Consistent with the findings observed in cystic fibrosis bronchial epithelial (CFBE) cells, F508del-expressing hBE cells also showed elevated HSF1-P and I-Hsp70 protein levels, as well as increased I-Hsp70 (HspA1A & A6), I-Hsp90, and I-Hsp40 mRNA levels, relative to that seen in WT-expressing hBEs (Figure 1H–1J). The gene discussed is HSF1; the disease is cystic fibrosis.