CCN4 and non-small cell lung carcinoma: As shown in Figure 1, WISP1 rs2929965 polymorphism was related to the overall toxicity of NSCLC patients in the additive model; WISP1 rs2929969 and rs2929973 were related to the overall toxicity of SCLC in additive and dominant models and related to the toxicity of NSCLC in the dominant model.