CCN4 and lung carcinoma: In conclusion, our results showed that WISP1 polymorphisms of (rs16893344, rs2929970, rs2977549, rs2977551, rs2929946, rs2977519, rs2977536, rs3739262, rs754958, rs2929965, rs2929969, rs2929973) were significantly associated with the chemotherapy toxicity of lung cancer patients.