In a Finnish study, conducted among patients, a 10-day forest fire smoke transport episode from Russia increased median values of IL-12 in ischemic heart disease patients’ plasma by 227% but had no effect on other inflammatory markers such as IL-8, C-reactive protein, fibrinogen, white blood cell count and myeloperoxidase in blood circulation [75]. The gene discussed is CXCL8; the disease is coronary artery disorder.