Table 1 summarizes the relationship between the phosphorylation of STAT3 and the clinicopathological factors of the 78 SCCHN patients. The expression of the phosphorylation of STAT3 was significantly correlated with cervical lymph node metastasis and clinical stage (P < 0.05). We also analyzed the relationship between CCR7 and p-STAT3 expression in these 78 specimens. The results showed a positive correlation between them (Table 2). This evidence concerns the gene CCR7 and head and neck squamous cell carcinoma.