DCX and stroke disorder: In a subsequent study, the transplantation of human NPCs together with Matrigel into the lesioned neocortex of young adult (3 month-old) and aged (24 month-old) male Fisher-344 rats at 2 weeks after stroke stimulated neurogenesis in the SVZ ipsilateral to stroke, as demonstrated by increased numbers of cells expressing the early neuronal lineage marker Dcx at 60 days post-transplantation (Jin et al., 2011).